Common Name: Alendronate Sodium
How this drug works: Overall, Fosamax benefits bones by slowing down the rate of bone breakdown (resorption). The main way it accomplishes this is by coating bone surfaces in a way that inhibits the bone-dissolving actions of osteoclasts (cells involved in bone breakdown). Fosamax actually becomes part of the bone structure. The balance between bone breakdown and build-up switches in favor of build-up and this increases production of normal healthy bone in patients with osteoporosis.
Forms of this Drug: Can be taken as an oral solution or in the form of tablets.
Typical dosages: Follow directions on the prescription label. This drug may be prescribed for taking daily or weekly in the following fashion.
For treatment of osteoporosis in postmenopausal women or men:
For prevention of osteoporosis in postmenopausal women:
How To Take this Drug: Weekly dosages should be taken once a week on the same day every week. Weekly or daily tablets should be taken with a full glass of water (6 to 8 ounces). The liquid solution should be followed with at least two fluid ounces of plain water. Take first thing in the morning and do not eat or drink for 30 minutes after taking the drug. Do not lie down for at least 30 minutes and until after the first food of the day. In general, do not take any other type of supplement or medicine until later in the day, following your physician’s directions.
Special Considerations: Adequate intake of calcium and vitamin D from foods and/or supplements is required for this drug to work well. If you are planning to have dental work or oral surgery, discuss your use of alendronate with your dental care professionals in advance.
Possible side effects: When taken according to directions, this drug is generally well tolerated. The most common complaints are for abdominal pain, heartburn or chest pain, and pain upon swallowing or difficulty swallowing. Less common problems include pain in bone, muscle, or joints. However, people in the drug studies who were taking the placebo pills had similar rates of these complaints. Any side effects should be reported immediately to your health care professional. Any dental or jaw pain is especially important to report to your doctor.
See additional information on alendronate in About.com Drug Finder.
NOTE: This information is not intended to cover all possible uses, precautions, interactions, or adverse effects for this drug. If you have questions about the drug(s) you are taking, check with your health care professional.